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Busulfan oral/injection and EQL Daytime Cold/Flu Relief

Determining the interaction of Busulfan oral/injection and EQL Daytime Cold/Flu Relief and the possibility of their joint administration.

Check result:

Busulfan oral/injection <> EQL Daytime Cold/Flu Relief

Relevance: 23.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using acetaminophen together with busulfan may increase the effects of busulfan. If your doctor prescribes these two drugs, you may need a dose adjustment or special tests to safely use both. Contact your doctor if you notice any of the side effects of busulfan, which may include bleeding or bruising, seizures, fever or chills, persistent cough, congestion, or breathing problems. You may also notice pain in the stomach or back, nausea, vomiting, or diarrhea. Also, these can be accompanied by decreased appetite or weight loss. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Theoretically, coadministration with acetaminophen may increase the plasma concentrations of busulfan. The proposed mechanism is decreased busulfan clearance via conjugation due to reduced levels of glutathione in blood and tissues caused by acetaminophen.

MANAGEMENT: Patients receiving busulfan therapy should be monitored more closely for toxicity (e.g., myelosuppression, seizures) if acetaminophen is administered concurrently. When busulfan is administered intravenously, acetaminophen should preferably be avoided within 72 hours prior to and during infusion of busulfan to minimize risk of an interaction.

References

"Product Information. Busulfex (busulfan)." ESP Pharma Inc, Edison, NJ.

Busulfan oral/injection

Generic Name: busulfan

Brand name: Busulfex, Myleran

Synonyms: Busulfan (oral/injection), Busulfan

What is Busulfan oral/injection?

EQL Daytime Cold/Flu Relief

Generic Name: acetaminophen / dextromethorphan / pseudoephedrine

Brand name: Alka-Seltzer Plus Flu/Body, DayQuil Multi-Symptom Cold/Flu, EQ Daytime Cold/Flu Relief, EQ Flu Relief, EQL Daytime Cold/Flu Relief, Tylenol Flu Maximum Strength, Sudafed Severe Cold, Tylenol Cold and Flu No Drowsiness Powder, Tylenol Cold No Drowsiness, Theraflu No Drowsiness Maximum Strength, Triaminic Sore Throat Formula, Contac Severe Cold and Flu Non Drowsy, Tylenol Cough Liquid with Decongestant, DayQuil, Day Time Multi Symptom, Triaminic Cold and Fever Formula, Sudafed Decongestant Cold and Cough, Tylenol Cold Severe Congestion, Tylenol Infants Cold Plus Cough, Robitussin Honey Flu, Extra Strength Tylenol Flu Daytime, Non-Drowsy Super Strength Contac Complete, Contact Cold and Sore Throat, Tylenol Cold & Flu Severe Day Time, Vicks Dayquil Daytime Cold/Flu, Triaminic Cough & Sore Throat, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Softchews Cough & Sore Throat, Day Relief Cold and Flu, Tylenol Cold & Flu Daytime, Tylenol Cold Non-Drowsy Caplets, Tylenol Cold Non-Drowsy Gelcaps, Daytime Cold and Flu Relief, Daytime Non-Drowsy, Theraflu Daytime Severe Cold, Severe Cold Multi-Sympton

Synonyms: n.a.

What is EQL Daytime Cold/Flu Relief?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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