Butabarbital and Propafenone
Determining the interaction of Butabarbital and Propafenone and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Some barbiturates increase the hepatic metabolism of propafenone. Plasma levels and efficacy of propafenone may be decreased. Data are available for phenobarbital. Propafenone efficacy should be monitored during coadministration, and plasma propafenone levels should be checked as necessary. It may be necessary to increase propafenone dosage.
- Chan GL, Axelson JE, Kerr CR "The effect of phenobarbital on the pharmacokinetics of propafenone in man." Pharm Res 5 (1988): s153
Generic Name: butabarbital
Brand name: Butisol Sodium, Busodium
Synonyms: n.a.
Generic Name: propafenone
Brand name: Rythmol, Rythmol SR
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Butabarbital-Propafenone Extended Release Capsule
- Butabarbital-Propafenone Hydrochloride
- Butabarbital-Propafenone Sustained-Release Capsules
- Butabarbital-Propafenone Tablets
- Butabarbital-Propantheline
- Butabarbital-Propantheline Bromide
- Propafenone-Butalbital and Acetaminophen
- Propafenone-Butalbital and Acetaminophen Capsule
- Propafenone-Butalbital Compound
- Propafenone-Butalbital, Acetaminophen and Caffeine Capsule
- Propafenone-Butalbital, acetaminophen, and caffeine
- Propafenone-Butalbital, Acetaminophen, and Caffeine Capsules and Tablets