Butalbital, Aspirin, and Caffeine and NexIUM 24HR (Esomeprazole Delayed-Release Tablets)
Determining the interaction of Butalbital, Aspirin, and Caffeine and NexIUM 24HR (Esomeprazole Delayed-Release Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has reported that coadministration of caffeine and aspirin lead to a 25% increase in the rate of appearance and 17% increase in maximum concentration of salicylate in the plasma. A significantly higher area under the plasma concentration time curve of salicylate was also reported when both drugs were administered together. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that coadministration of aspirin and caffeine may lead to higher salicylate levels faster.
- Yoovathaworn KC, Sriwatanakul K, Thithapandha A "Influence of caffeine on aspirin pharmacokinetics." Eur J Drug Metab Pharmacokinet 11 (1986): 71-6
Generic Name: aspirin / butalbital / caffeine
Brand name: Butalbital Compound, Fiorinal, Fiormor, Fiortal, Fortabs, Idenal, Laniroif
Synonyms: Aspirin, butalbital, and caffeine
Generic Name: esomeprazole
Brand name: NexIUM 24HR, Esomeprazole Strontium, Nexium, Nexium, Nexium IV
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Butalbital, Aspirin, and Caffeine-Nexium Capsules
- Butalbital, Aspirin, and Caffeine-Nexium I.V.
- Butalbital, Aspirin, and Caffeine-Nexium I.V. Injection
- Butalbital, Aspirin, and Caffeine-Nexium Oral
- Butalbital, Aspirin, and Caffeine-Nexplanon
- Butalbital, Aspirin, and Caffeine-Next Choice
- NexIUM 24HR (Esomeprazole Delayed-Release Tablets)-Butalbital, Aspirin, Caffeine, and Codeine
- NexIUM 24HR (Esomeprazole Delayed-Release Tablets)-Butalbital,Aspirin and Caffeine Capsule
- NexIUM 24HR (Esomeprazole Delayed-Release Tablets)-Butapap
- NexIUM 24HR (Esomeprazole Delayed-Release Tablets)-Butisol
- NexIUM 24HR (Esomeprazole Delayed-Release Tablets)-Butisol Sodium
- NexIUM 24HR (Esomeprazole Delayed-Release Tablets)-Butorphanol