Butisol and Solifenacin
Determining the interaction of Butisol and Solifenacin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Butabarbital may reduce the blood levels and effects of solifenacin. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Theoretically, coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of solifenacin, which has been shown to be a substrate of the isoenzyme in vitro.
MANAGEMENT: Pharmacologic response to solifenacin should be monitored more closely whenever a CYP450 3A4 inducer is added to or withdrawn from therapy, and the solifenacin dosage adjusted if necessary.
- "Product Information. VESIcare (solifenacin)." GlaxoSmithKline, Research Triangle Park, NC.
Generic Name: butabarbital
Brand name: Butisol Sodium, Busodium
Synonyms: Butabarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Butisol-Solifenacin Succinate
- Butisol-Solifenacin Tablets
- Butisol-Soliqua
- Butisol-Soliqua 100/33
- Butisol-Soliris
- Butisol-Solmara Patch
- Solifenacin-Butisol Sodium
- Solifenacin-Butorphanol
- Solifenacin-Butorphanol injection
- Solifenacin-Butorphanol Injection Solution
- Solifenacin-Butorphanol nasal
- Solifenacin-Butorphanol Nasal Solution