Butisol Sodium and Vfend Tablets
Determining the interaction of Butisol Sodium and Vfend Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Butabarbital may reduce the blood levels of voriconazole, which may make the medication less effective in treating your fungal infection. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inducers of CYP450 isoenzymes may decrease the plasma concentrations of voriconazole, which is metabolized by CYP450 2C19, 2C9, and/or 3A4.
MANAGEMENT: The potential for diminished pharmacologic effects of voriconazole should be considered during coadministration with CYP450 inducers. Alternative treatments may be required if an interaction is suspected.
- "Product Information. VFEND (voriconazole)." Pfizer U.S. Pharmaceuticals, New York, NY.
Generic Name: butabarbital
Brand name: Butisol Sodium, Busodium
Synonyms: n.a.
Generic Name: voriconazole
Brand name: Vfend, Vfend
Synonyms: Vfend, Vfend Injection
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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