Butorphanol Injection Solution and Cimetidine Tablets
Determining the interaction of Butorphanol Injection Solution and Cimetidine Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Cimetidine may increase the blood levels and effects of butorphanol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience dizziness, fainting, confusion, excessive drowsiness, slow heart rate, shallow or difficult breathing, and/or shortness of breath. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Cimetidine may increase the action of narcotic analgesics. Cases of respiratory depression and apnea have been reported. The mechanism is unknown.
MANAGEMENT: Patients' vital signs should be closely monitored while receiving this combination. If clinically significant respiratory depression occurs, the drugs should be withdrawn. The use of a narcotic antagonist, such as naloxone, may be needed.
- Lam AM "Potentially lethal interaction of cimetidine and morphine." Can Med Assoc J 125 (1981): 820
- Fine A, Churchill DN "Potentially lethal interaction of cimetidine and morphine." Can Med Assoc J 124 (1981): 1434, 1436
- Lam AM, Clement JL "Effect of cimetidine premedication on morphine-induced ventilatory depression." Can Anaesth Soc J 31 (1984): 36-43
Generic Name: butorphanol
Brand name: Stadol, Stadol NS
Synonyms: Butorphanol (injection), Butorphanol
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Butorphanol Injection Solution-Cimzia
- Butorphanol Injection Solution-Cimzia (Certolizumab Prefilled Syringes)
- Butorphanol Injection Solution-Cimzia (Certolizumab Vials)
- Butorphanol Injection Solution-Cinacalcet
- Butorphanol Injection Solution-Cinacalcet Hydrochloride
- Butorphanol Injection Solution-Cinobac
- Cimetidine Tablets-Butorphanol nasal
- Cimetidine Tablets-Butorphanol Nasal Solution
- Cimetidine Tablets-Butorphanol Nasal Spray
- Cimetidine Tablets-Butorphanol Tartrate
- Cimetidine Tablets-Butrans
- Cimetidine Tablets-Butrans Patch