Butrans and Niraparib Tosylate

• Generic Name: buprenorphine
• Dosage Forms: patch, extended release
• Other Brand Names: Butrans, Belbuca, Buprenex, Probuphine, Sublocade, Subutex

Butrans skin patches contain buprenorphine, an opioid pain medication. An opioid is sometimes called a narcotic.

Butrans skin patches are used for around-the-clock treatment of moderate to severe chronic pain that is not controlled by other medicines.

Butrans is not for use on an as-needed basis for pain.

• Generic Name: niraparib
• Dosage Forms: n.a.
• Other Brand Names: Zejula

Maintenance therapy of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients in complete or partial response following platinum-based chemotherapy (designated an orphan drug by FDA for this use).

In the principal efficacy study (NOVA), niraparib maintenance therapy substantially prolonged progression-free survival in patients with platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancer compared with placebo regardless of the presence or absence of germline BRCA mutations or homologous recombination deficiency (HRD) status.