Bydureon and Digoxin Injection
Determining the interaction of Bydureon and Digoxin Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with exenatide may modestly affect the pharmacokinetic disposition of digoxin. The mechanism of interaction has not been described. Following repeated doses of exenatide (10 mcg twice a day), the peak plasma concentration (Cmax) of digoxin (0.25 mg orally once a day) was decreased by 17% and the time to reach peak plasma concentration (Tmax) was delayed by approximately 2.5 hours. However, the overall steady-state digoxin pharmacokinetic exposure (AUC) was unaltered.
- "Product Information. Byetta (exenatide)." Amylin Pharmaceuticals Inc, San Diego, CA.
Generic Name: exenatide
Brand name: Bydureon, Bydureon BCise, Bydureon Pen, Bydureon Tray, Byetta Prefilled Pen
Synonyms: n.a.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bydureon-Digoxin Intravenous
- Bydureon-Digoxin Oral Solution
- Bydureon-Digoxin oral/injection
- Bydureon-Digoxin Tablets
- Bydureon-Dihydro CP Syrup
- Bydureon-Dihydrocodeine BPM Phenyleph HCl
- Digoxin Injection-Bydureon (Exenatide Extended-Release Injection (Bydureon) (Pens))
- Digoxin Injection-Bydureon (Exenatide Extended-Release Injection (Bydureon) (Trays))
- Digoxin Injection-Bydureon BCise
- Digoxin Injection-Bydureon Pen
- Digoxin Injection-Byetta
- Digoxin Injection-Bystolic