Bydureon BCise and Mekinist

• Generic Name: exenatide
• Dosage Forms: injection, suspension, extended release
• Other Brand Names: Bydureon BCise, Bydureon Pen, Bydureon Tray, Bydureon, Byetta Prefilled Pen

This medication guide provides information about the Bydureon brand of exenatide. Byetta is another brand of exenatide that is not covered in this medication guide.

Bydureon BCise is an injectable diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin more efficiently. Bydureon is a long-acting form of exenatide.

Bydureon is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Bydureon is not for treating type 1 diabetes.

Bydureon may also be used for purposes not listed in this medication guide.

• Generic Name: trametinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Mekinist

Mekinist (trametinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Mekinist is used alone or in combination with another medicine called dabrafenib (Tafinlar) to treat certain types of cancer in people who have a "BRAF" gene mutation.

Mekinist is for use in treating:

• melanoma (skin cancer) that cannot be treated with surgery or has spread to other parts of the body, or to prevent melanoma from coming back after surgery;

• non-small cell lung cancer that has spread to other parts of the body; or

• advanced or metastatic thyroid cancer that has spread and for which there are no other treatment options.