Bydureon (Exenatide Extended-Release Injection (Bydureon) (Trays)) and Naltrexone Hydrochloride And Bupropion Hydrochloride

• Generic Name: exenatide
• Dosage Forms: n.a.
• Other Brand Names:

  Byetta Prefilled Pen, Bydureon, Bydureon BCise, Bydureon Pen, Bydureon Tray

• It is used to lower blood sugar in patients with high blood sugar (diabetes).

• Generic Name: bupropion / naltrexone
• Dosage Forms: n.a.
• Other Brand Names: Contrave

Naltrexone hydrochloride and bupropion hydrochloride is a fixed combination of naltrexone, an opioid antagonist, and bupropion, an aminoketone antidepressant, and is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

The effect of naltrexone hydrochloride and bupropion hydrochloride on cardiovascular morbidity and mortality has not been established.

The safety and effectiveness of naltrexone hydrochloride and bupropion hydrochloride in combination with other products intended for weight loss, including prescription and over-the-counter drugs and herbal preparations, have not been established.