Bydureon Pen and Turmeric

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.MONITOR: Coadministration of turmeric with antidiabetic drugs might potentiate the risk of hypoglycemia. Some small studies have shown that curcumin, the main component in turmeric, can reduce the blood levels of glucose and/or glycosylated hemoglobin (HbA1C) in diabetic patients. In a pharmacokinetic study involving eight type-2 diabetic patients, curcumin (475 mg daily) also increased glyburide (5 mg daily) blood levels by 12% at 2 hours after glyburide administration. The combination of glyburide and curcumin significantly decreased plasma glucose levels for up to 24 hours compared to glyburide alone. However, no patient experienced hypoglycemia. MANAGEMENT: Blood glucose should be monitored, and patients should be educated on the potential signs and symptoms of hypoglycemia (e.g., headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, palpitation, and tachycardia) and appropriate remedial actions to take if it occurs. Patients should also be advised to take precautions to avoid hypoglycemia while driving or operating hazardous machinery. References Hodaei H, Adibian M, Nikpayam O, Hedayati M, Sohrab G "The effect of curcumin supplementation on anthropometric indices, insulin resistance and oxidative stress in patients with type 2 diabetes: a randomized, double-blind clinical trial." Diabet Metab Syndr 11 (2019): e-collection 2019 Adibian M, Hodaei H, Nikpayam O, Sohrab G, Hekmatdoost A, Hedayati M "The effects of curcumin supplementation on high-sensitivity C-reactive protein, serum adiponectin, and lipid profile in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial." Phytother Res 33 (2019): 1374-83 Neerati R, Devde R, Gangi AK "Evaluation of the effects of curcumin capsules on glyburide therapy in patients with type-2 diabetes mellitus." Phytother Res 28 (2014): 1796-1800 Chuengsamarn S, Rattanamongkolgul s, Luechapudiporn R, Phisalaphong C, Jirawatnotai S "Curcumin extract for prevention of type 2 diabetes." Diabetes Care 35 (2012): 2121-7 View all 4 references

MONITOR: Coadministration of turmeric with antidiabetic drugs might potentiate the risk of hypoglycemia. Some small studies have shown that curcumin, the main component in turmeric, can reduce the blood levels of glucose and/or glycosylated hemoglobin (HbA1C) in diabetic patients. In a pharmacokinetic study involving eight type-2 diabetic patients, curcumin (475 mg daily) also increased glyburide (5 mg daily) blood levels by 12% at 2 hours after glyburide administration. The combination of glyburide and curcumin significantly decreased plasma glucose levels for up to 24 hours compared to glyburide alone. However, no patient experienced hypoglycemia.

MANAGEMENT: Blood glucose should be monitored, and patients should be educated on the potential signs and symptoms of hypoglycemia (e.g., headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, palpitation, and tachycardia) and appropriate remedial actions to take if it occurs. Patients should also be advised to take precautions to avoid hypoglycemia while driving or operating hazardous machinery.

Bydureon Pen

Generic Name: exenatide

Brand name: Bydureon, Bydureon BCise, Bydureon Pen, Bydureon Tray, Byetta Prefilled Pen

Synonyms: Bydureon

What is Bydureon Pen?

Turmeric

Generic Name: turmeric

Brand name:

Synonyms: n.a.

What is Turmeric?