C-500 and Hydrocodone and Pseudoephedrine
Determining the interaction of C-500 and Hydrocodone and Pseudoephedrine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Acidic urine increases the elimination of ephedrine and pseudoephedrine and decreases the elimination half-life. The clinical significance is unknown. The therapeutic effects of these agents may be decreased.
- Wilkinson GR, Beckett AH "Absorption metabolism and excretion of the ephedrines in man. I. The influence of urinary pH and urine volume output." J Pharmacol Exp Ther 162 (1968): 139-47
- Brater DC, Kaojarern S, Benet LZ, et al "Renal excretion of pseudoephedrine." Clin Pharmacol Ther 28 (1980): 690-4
- Kuntzman RG, Tsai I, Brand L, Mark LC "The influence of urinary pH on the plasma half-life of pseudoephedrine in man and dog and a sensitive assay for its determination in human plasma." Clin Pharmacol Ther 12 (1971): 62-7
Generic Name: ascorbic acid
Brand name: Acerola, Ascorbic Acid Quick Melts, C/Rose Hips, Cecon, Cemill 500, C-Time, Ester-C, N Ice with Vitamin C, Sunkist Vitamin C, Vasoflex HD, Vicks Vitamin C Drops, Vitamin C, Cenolate, Mega-C-Acid Plus, Cee-500, C-500-Gr, Centrum Singles-Vitamin C, Ascot, Cevi-Bid, Vitamin C TR, Vitamin C with Rose Hips, Cemill 1000, Ascor L NC, Ascor, Ascor L 500, Betac, Cemill, Protexin
Synonyms: C-500 (Oral)
Generic Name: hydrocodone / pseudoephedrine
Brand name: Rezira
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- C-500-Hydrocodone Bitartrate
- C-500-Hydrocodone Bitartrate and Acetaminophen Oral Solution
- C-500-Hydrocodone Extended-Release Capsules
- C-500-Hydrocodone Extended-Release Tablets
- C-500-Hydrocodone Polistirex and Chlorpheniramine Polistirex Suspension
- C-500-Hydrocodone, Chlorpheniramine, and Pseudoephedrine
- Hydrocodone and Pseudoephedrine-C-Nate DHA
- Hydrocodone and Pseudoephedrine-C-Tanna 12
- Hydrocodone and Pseudoephedrine-C-Time
- Hydrocodone and Pseudoephedrine-C-Time w/Rose Hips
- Hydrocodone and Pseudoephedrine-C-Topical
- Hydrocodone and Pseudoephedrine-C-Topical Solution