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Cafergot (Ergotamine and Caffeine Suppositories) and Zorbtive

Determining the interaction of Cafergot (Ergotamine and Caffeine Suppositories) and Zorbtive and the possibility of their joint administration.

Check result:
Cafergot (Ergotamine and Caffeine Suppositories) <> Zorbtive
Relevance: 18.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Somatropin may reduce the blood levels and effects of ergotamine. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of ergot alkaloids, which are substrates of the isoenzyme.

MANAGEMENT: The potential for diminished therapeutic effects of ergot alkaloids should be considered when used in combination with CYP450 3A4 inducers.

References
  • "Product Information. Methergine (methylergonovine)." Novartis Pharmaceuticals, East Hanover, NJ.
Cafergot (Ergotamine and Caffeine Suppositories)

Generic Name: caffeine / ergotamine

Brand name: Cafergot, Migergot, Wigraine, Cafetrate, Ercaf, Cafatine

Synonyms: Cafergot (Suppositories), Cafergot

Zorbtive

Generic Name: somatropin

Brand name: Genotropin, Genotropin Miniquick, Humatrope, Norditropin FlexPro Pen, Norditropin Nordiflex Pen, Nutropin AQ NuSpin 10, Nutropin AQ Pen 10 Cartridge, Omnitrope, Saizen, Serostim, Tev-Tropin, Zomacton, Zorbtive, Nutropin, Norditropin, Nutropin AQ, Nutropin Depot, Norditropin Cartridge, Saizen Click-Easy, Omnitrope Pen 5 Cartridge, HumatroPen, Omnitrope Pen 10 Cartridge, Nutropin AQ Pen 20 Cartridge, Nutropin AQ NuSpin 5, Nutropin AQ NuSpin 20, Saizen Kit

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.