Cafergot (Ergotamine and Caffeine Tablets) and Sumycin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Medications like tetracycline may rarely increase the effects of ergotamine, leading to excessive narrowing of blood vessels in the body. This can reduce blood flow to vital organs and increase the risk of serious side effects such as high blood pressure, heart attack, stroke, and gangrene (death of tissues, usually in the arm or leg, that may require surgical amputation). You should seek immediate medical attention if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech during treatment with ergotamine. Do not take larger doses or use the drug more frequently than prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Limited data suggest that tetracyclines may increase the plasma concentrations and toxicity of ergot alkaloids. The mechanism is unknown, but may be related to tetracycline effects on liver function. Several cases of ergotism have been reported in patients taking ergotamine or dihydroergotamine with a tetracycline.

MANAGEMENT: Caution may be advisable when ergot alkaloids are prescribed in combination with tetracyclines. Patients should be monitored for potential ergot toxicity including peripheral vasospasm, ischemia, thrombosis, tachycardia, and hypertension. Patients should be advised to notify their physician if they experience potential signs and symptoms of ergotism such as paraesthesia, cyanosis, cold or painful extremities, muscle pain or weakness, abdominal pain, irregular heartbeat, and chest pain or tightness.

Cafergot (Ergotamine and Caffeine Tablets)

Generic Name: caffeine / ergotamine

Brand name: Cafergot, Migergot, Wigraine, Cafetrate, Ercaf, Cafatine

Synonyms: Cafergot (Suppositories), Cafergot

What is Cafergot (Ergotamine and Caffeine Tablets)?

Sumycin

Generic Name: tetracycline

Brand name: Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap, Tetracon, Robitet 500, Emtet-500

Synonyms: n.a.

What is Sumycin?