Cafergot Tablets and Topcare Aspirin
Determining the interaction of Cafergot Tablets and Topcare Aspirin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has reported that coadministration of caffeine and aspirin lead to a 25% increase in the rate of appearance and 17% increase in maximum concentration of salicylate in the plasma. A significantly higher area under the plasma concentration time curve of salicylate was also reported when both drugs were administered together. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that coadministration of aspirin and caffeine may lead to higher salicylate levels faster.
- Yoovathaworn KC, Sriwatanakul K, Thithapandha A "Influence of caffeine on aspirin pharmacokinetics." Eur J Drug Metab Pharmacokinet 11 (1986): 71-6
Generic Name: caffeine / ergotamine
Brand name: Cafergot, Migergot, Wigraine, Cafetrate, Ercaf, Cafatine
Synonyms: Cafergot (Suppositories), Cafergot
Generic Name: aspirin
Brand name: Arthritis Pain, Aspir 81, Aspir-Low, Bayer Childrens Aspirin, Durlaza, Ecotrin, Ecpirin, Fasprin, Halfprin, Miniprin, Aspiritab, Bayer, Bayer Low Strength, Bayer Children's, St. Joseph 81 mg Adult
Synonyms: Aspirin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cafergot Tablets-Topcare Childrens All Day Allergy
- Cafergot Tablets-Topcare Childrens Allergy Relief 24 Hour
- Cafergot Tablets-Topcare ClearLax
- Cafergot Tablets-Topcare Complete Acid Reducer plus Antacid
- Cafergot Tablets-Topcare Cough and Sore Throat
- Cafergot Tablets-Topcare Dayhist Allergy
- Topcare Aspirin-Caffeine
- Topcare Aspirin-Caffeine and ergotamine oral/rectal
- Topcare Aspirin-Caffeine and sodium benzoate Injection
- Topcare Aspirin-Caffeine Capsules and Tablets
- Topcare Aspirin-Caffeine Citrate
- Topcare Aspirin-Caffeine Citrate Injection Solution