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Caffeine and ergotamine oral/rectal and Valium

Determining the interaction of Caffeine and ergotamine oral/rectal and Valium and the possibility of their joint administration.

Check result:

Caffeine and ergotamine oral/rectal <> Valium

Relevance: 20.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

One study has reported a 22% reduction in diazepam plasma levels when coadministered with caffeine. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that changes to caffeine consumption habits may impact the efficacy of diazepam therapy.

References

Ghoneim MM, Hinrichs JV, Chiang CK, Loke WH "Pharmacokinetic and pharmacodynamic interactions between caffeine and diazepam." J Clin Psychopharmacol 6 (1986): 75-80

Caffeine and ergotamine oral/rectal

Generic Name: caffeine / ergotamine

Brand name: Cafergot, Migergot, Wigraine, Cafetrate, Ercaf, Cafatine

Synonyms: Caffeine and ergotamine (oral/rectal), Ergotamine and Caffeine

What is Caffeine and ergotamine oral/rectal?

Valium

Generic Name: diazepam

Brand name: Valium, Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Zetran

Synonyms: n.a.

What is Valium?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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