Caffeine and sodium benzoate Injection and Ropivacaine Hydrochloride
Determining the interaction of Caffeine and sodium benzoate Injection and Ropivacaine Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Ropivacaine serum concentrations may increase when given with drugs metabolized by the CYP450 isoenzyme 1A2. The theorized mechanism is via competitive inhibition. Information is only available from in-vitro studies. The clinical significance is unknown. Consider monitoring the patient more closely for prolonged or excessive ropivacaine effects if these agents are coadministered.
- "Product Information. Naropin (ropivacaine)." Astra USA, Westborough, MA.
Generic Name: caffeine / sodium benzoate
Brand name: Cafcit, No Doz, Vivarin
Synonyms: Caffeine and sodium benzoate (Injection)
Generic Name: ropivacaine
Brand name: Naropin, Naropin Polyamp, Naropin SDV, Naropin Novaplus
Synonyms: Ropivacaine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Ropivacaine Hydrochloride-Caffeine Capsules and Tablets
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- Ropivacaine Hydrochloride-Caffeine; Caffeine and Sodium Benzoate Injection; Caffeine Citrate