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Calan and Roxanol

Determining the interaction of Calan and Roxanol and the possibility of their joint administration.

Check result:

Calan <> Roxanol

Relevance: 07.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

One study of polysubstance abusers has suggested that verapamil may attenuate the euphoragenic effects of morphine and potentiate the analgesic effects. The clinical implications of this interaction for patients with pain are unknown.

References

Vaupel DB, Lange WR, London ED "Effects of verapamil on morphine-induced euphoria, analgesia and respiratory depression in humans." J Pharmacol Exp Ther 267 (1993): 1386-94

Calan

Generic Name: verapamil

Brand name: Calan, Calan SR, Isoptin SR, Verelan, Isoptin, Isoptin IV, Covera-HS, Verelan PM

Synonyms: Calan Immediate-Release Tablets

What is Calan?

Roxanol

Generic Name: morphine

Brand name: Roxanol, Arymo ER, Kadian, MorphaBond ER, Avinza, MS Contin, Duramorph PF, Infumorph, Mitigo, RMS

Synonyms: n.a.

What is Roxanol?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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