Calcijex and Diphenhydramine and magnesium salicylate
Determining the interaction of Calcijex and Diphenhydramine and magnesium salicylate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using calcitriol together with magnesium salicylate can lead to elevated magnesium blood levels, particularly in individuals with reduced kidney function. Symptoms of high magnesium levels may include nausea, vomiting, flushing, drowsiness, dizziness, confusion, muscle weakness, reduced reflexes, low blood pressure, slow heart rate, and impaired breathing. You should seek medical attention if you experience these symptoms. If you are on dialysis and treated with calcitriol or other vitamin D medications, you should generally avoid taking products that contain magnesium without first talking to your doctor, as high levels of magnesium over time can lead to bone problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to potentially additive pharmacologic effects. Chronic hypermagnesemia may have a role in the pathogenesis of adynamic bone disease in dialysis patients.
MANAGEMENT: Patients on chronic renal dialysis treated with a vitamin D analog should avoid magnesium-containing products.
- "Product Information. Zemplar (paricalcitol)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Hectorol (doxercalciferol)." Genzyme Corporation, Cambridge, MA.
- "Product Information. One-Alpha (alfacalcidol)." Pharmel Inc, Montreal, IN.
- "Product Information. Rocaltrol (calcitriol)." Roche Laboratories, Nutley, NJ.
Generic Name: diphenhydramine / magnesium salicylate
Brand name: Doans PM
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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