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Calcitrate and Digoxin

Determining the interaction of Calcitrate and Digoxin and the possibility of their joint administration.

Check result:
Calcitrate <> Digoxin
Relevance: 03.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Excessive blood levels of calcium can increase the effects of digoxin. Do not exceed the dosage of calcium citrate prescribed by your doctor or recommended on the product labeling. You should also check with your doctor before using any over-the-counter products that contain calcium, such as vitamin supplements or antacids. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Excessive administration of calcium can aggravate digitalis toxicity and precipitate serious cardiac arrhythmias in digitalised patients. The mechanism probably involves additive or synergistic inotropic effects of calcium and digitalis glycosides on the myocardium.

MANAGEMENT: Caution is advised if calcium preparations are used in patients receiving digitalis glycosides. Patients should be advised not to exceed the calcium dosage prescribed for them and to consult their healthcare provider before consuming additional products that may contain substantial amounts of calcium (e.g., over-the-counter supplements).

References
  • "Product Information. PhosLo (calcium acetate)" Braintree, Braintree, MA.
Calcitrate

Generic Name: calcium citrate

Brand name: Calcitrate, Citracal, Cit Calcium, Citracal Liquitab

Synonyms: n.a.

Digoxin

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction