Calcitriol Ointment and Zevalin

• Generic Name: calcitriol topical
• Dosage Forms: ointment
• Other Brand Names: Vectical

Calcitriol is a form of vitamin D.

Calcitriol topical (for the skin) is used to treat plaque psoriasis (raised, silvery flaking of the skin) in adults.

Calcitriol topical is not for use in treating severe forms of psoriasis (with pus, skin peeling, severe redness).

Calcitriol topical may also be used for purposes not listed in this medication guide.

• Generic Name: ibritumomab
• Dosage Forms: injection
• Other Brand Names: Y-90 Zevalin, In-111 Zevalin

Part of a specific therapeutic regimen (ibritumomab tiuxetan therapeutic regimen) for treatment of relapsed or refractory low-grade or follicular B-cell non-Hodgkin’s lymphoma (NHL) (designated an orphan drug by FDA for this use). Safety and efficacy not evaluated in patients with ≥25% involvement of bone marrow by lymphoma and/or impaired bone marrow reserve (e.g., prior myeloablative therapies, prior external beam radiation to >25% of active marrow, neutrophil count <1500/mm3).

Ibritumomab tiuxetan therapeutic regimen also used for consolidation treatment of newly diagnosed follicular NHL in patients who have achieved partial or complete response to first-line induction chemotherapy. Safety and efficacy not evaluated in patients with ≥25% involvement of bone marrow by lymphoma and/or impaired bone marrow reserve (e.g., prior myeloablative therapies, prior external beam radiation to >25% of active marrow, platelet count <150,000/mm3).