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Calcium and Vitamin D Capsules and Tablets and Kenalog-40

Determining the interaction of Calcium and Vitamin D Capsules and Tablets and Kenalog-40 and the possibility of their joint administration.

Check result:
Calcium and Vitamin D Capsules and Tablets <> Kenalog-40
Relevance: 23.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Antacids and agents with acid-neutralizing effects may impair the absorption of dexamethasone, prednisolone, prednisone, and other corticosteroids, although data from published studies are somewhat conflicting. The mechanism of interaction and clinical significance are unknown. No particular intervention is necessary during concomitant therapy with these agents, but clinicians should be aware of the potential for interaction.

References
  • Naggar VF, Khalil SA, Gouda MW "Effect of concomitant administration of magnesium trisilicate on GI absorption of dexamethasone in humans." J Pharm Sci 67 (1978): 1029-30
  • Tanner AR, Caffin JA, Halliday JW, Powell LW "Concurrent administration of antacids and prednisone: effect on serum levels of prednisolone." Br J Clin Pharmacol 7 (1979): 397-400
  • Albin H, Vincon G, Demotes-Mainard F, et al "Effect of aluminium phosphate on the bioavailability of cimetidine and prednisolone." Eur J Clin Pharmacol 26 (1984): 271-3
Calcium and Vitamin D Capsules and Tablets

Generic Name: calcium / vitamin d

Brand name: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D, UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Caltrate 600 with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P & D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcitrate, Caltrate 600+D, Os-Cal 500+D, Os-Cal 500+Extra D Chewable

Synonyms: Calcium and vitamin D combination

Kenalog-40

Generic Name: triamcinolone

Brand name: Kenalog-40, Zilretta, Aristocort, Azmacort

Synonyms: Kenalog-40 (injection)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.