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Calcium Carbonate and Simethicone and Estramustine Phosphate Sodium

Determining the interaction of Calcium Carbonate and Simethicone and Estramustine Phosphate Sodium and the possibility of their joint administration.

Check result:
Calcium Carbonate and Simethicone <> Estramustine Phosphate Sodium
Relevance: 18.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using calcium carbonate together with estramustine may decrease the effects of estramustine. Administration of estramustine should be separated at least 1 hour before or 2 hours after meals, milk, or calcium carbonate. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Oral calcium containing products may significantly decrease serum concentrations of estramustine. The mechanism of the interaction is not known.

MANAGEMENT: Estramustine should be taken at least 1 hour before or 2 hours after meals, milk, or calcium containing products.

References
  • "Product Information. Emcyt (estramustine)." Pharmacia and Upjohn, Kalamazoo, MI.
Calcium Carbonate and Simethicone

Generic Name: calcium carbonate / simethicone

Brand name: Alka-Seltzer Heartburn + Gas, Gas-X with Maalox Extra Strength, Maalox Advanced Maximum Strength, Maalox Junior Plus Antigas, Tums Gas Relief Chewy Bites

Synonyms: n.a.

Estramustine Phosphate Sodium

Generic Name: estramustine

Brand name: Emcyt

Synonyms: Estramustine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.