Calcium carbonate, magnesium hydroxide, and simethicone and Fexofenadine
Determining the interaction of Calcium carbonate, magnesium hydroxide, and simethicone and Fexofenadine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using fexofenadine together with magnesium hydroxide may decrease the effects of fexofenadine. Fexofenadine should be administered at least 2 hours before magnesium hydroxide. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: The concomitant administration of aluminum or magnesium-containing antacids with fexofenadine reduces its peak serum concentrations (Cmax) by 43% and area under the plasma concentration-time curve (AUC) by 41%. The clinical significance is unknown.
MANAGEMENT: Fexofenadine should be administered at least 2 hours before antacids.
- "Product Information. Allegra (fexofenadine)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: calcium carbonate / magnesium hydroxide / simethicone
Brand name: Mylanta Tonight
Synonyms: n.a.
Generic Name: fexofenadine
Brand name: Allegra, Aller-Ease, Children's Allegra Allergy, Mucinex Allergy, Wal-Fex, Allegra ODT, Allegra 24 Hour Allergy, Allegra Allergy, Children's Allegra ODT, Allergy Relief, Allegra OTC
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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