Calcium Carbonate Tablets (Antacid) and Sumatriptan and naproxen
Determining the interaction of Calcium Carbonate Tablets (Antacid) and Sumatriptan and naproxen and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Antacids and some oral aluminum, calcium, or magnesium containing preparations may decrease the gastrointestinal absorption of enteric-coated naproxen, which requires an acidic environment for dissolution. The proposed mechanism is an increase in gastric pH (i.e. decreased gastric acidity) produced by antacids. In patients treated with antacids, the possibility of a reduced or subtherapeutic response to enteric-coated naproxen should be considered. Concomitant use of these drugs is generally not recommended. Aluminum hydroxide and some magnesium-containing antacids have also been reported to reduce the absorption of regular naproxen. The interaction may be minimized by separating the times of administration by at least 2 hours.
- Segre EJ, Sevelius H, Varady J "Effects of antacids on naproxen absorption." N Engl J Med 291 (1974): 582-3
- Brogden RN, Heel RC, Speight TM, Avery GS "Naproxen up to date: a review of its pharmacological properties and therapeutic efficacy and use in rheumatic diseases and pain states." Drugs 18 (1979): 241-77
Generic Name: calcium carbonate
Brand name: Calci-Chew, Oysco 500, Calci Mix, Os-Cal 500, Oyst Cal 500, Oyster Shell Calcium 500, Nephro Calci, Amitone, Dicarbosil, Equilet, Tums, Chooz, Tums E-X, Alkets, Titralac, Oyster Cal 500, Calcitab, Oyster Shell, Oyster Calcium, Super Calcium, Calcium Concentrate, Caltro, Oyster, Oyster Cal, Cal Oys, Alkums, Cal-Gest, Tums 500, Tums Ultra, Alka-Mints, Calcarb, Caltrate, Rolaids Sodium Free, Amilac, Calcium Oyster, Oyst Cal, Calcium Liquid Softgel, Mylanta Child, Maalox Quick Dissolve, Maalox Quick Dissolve Maximum Strength, Ultra Mylanta Calci Tabs, Extra Strength Mylanta Calci Tabs, Os-Cal, Surpass, Surpass Extra Strength, Icar Prenatal Chewable Calcium, Tums Extra Strength, Maalox Quick Dissolve Extra Strength, Calcium Oyster Shell, Maalox Antacid Barrier, Rolaids Soft Chew, Pepto Children's, Maalox Regular Strength, Maalox Children's, Tums Kids, Tums QuikPak, Calci-Mix, Alcalak, Tums Smoothies, Tums Chewy Bites, Tums Chewy Delights, Tums Sugar-Free, Cal-Mint, Calci Mix, OsCal 500
Synonyms: Calcium carbonate, Calcium Carbonate
Generic Name: naproxen / sumatriptan
Brand name: Treximet
Synonyms: Sumatriptan and Naproxen
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Calcium Carbonate Tablets (Antacid)-Sumatriptan injection
- Calcium Carbonate Tablets (Antacid)-Sumatriptan Nasal Powder
- Calcium Carbonate Tablets (Antacid)-Sumatriptan Nasal Spray
- Calcium Carbonate Tablets (Antacid)-Sumatriptan Nasal, Oral, Subcutaneous
- Calcium Carbonate Tablets (Antacid)-Sumatriptan oral/nasal
- Calcium Carbonate Tablets (Antacid)-Sumatriptan Subcutaneous
- Sumatriptan and naproxen-Calcium carbonate, magnesium hydroxide, and simethicone
- Sumatriptan and naproxen-Calcium Carbonate/Vit D/Vit B6/Vit B12/Folic Acid with Minerals Chew Wafers
- Sumatriptan and naproxen-Calcium Chloride
- Sumatriptan and naproxen-Calcium citrate
- Sumatriptan and naproxen-Calcium Disodium Versenate
- Sumatriptan and naproxen-Calcium Folinate Injection