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Calcium Chloride and Lanoxin (Digoxin Injection)

Determining the interaction of Calcium Chloride and Lanoxin (Digoxin Injection) and the possibility of their joint administration.

Check result:
Calcium Chloride <> Lanoxin (Digoxin Injection)
Relevance: 14.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using digoxin together with calcium chloride. Taking these drugs together can affect the rhythm of your heart. Call your doctor if you have symptoms of irregular heartbeat, chest tightness, blurred vision, nausea, and seizures. You may need a dose adjustment or need your blood levels checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The administration of parenteral calcium preparations, particularly by rapid IV injection, may precipitate serious cardiac arrhythmias in digitalized patients. The mechanism is probably related to the additive or synergistic inotropic effects of calcium and digitalis glycosides on the myocardium.

MANAGEMENT: Intravenous calcium should preferably not be used in patients receiving digitalis glycosides, or it should be given slowly or in small amounts to avoid high serum calcium concentrations. Patients should be monitored for development of arrhythmias.

References
  • "Product Information. PhosLo (calcium acetate)" Braintree, Braintree, MA.
  • "Product Information. Calcium Gluconate (calcium gluconate)." Fresenius Kabi USA, LLC, Lake Zurich, IL.
  • "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Calcium Chloride

Generic Name: calcium chloride

Brand name:

Synonyms: n.a.

Lanoxin (Digoxin Injection)

Generic Name: digoxin

Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin

Synonyms: Lanoxin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle