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Caldolor and Tacrine

Determining the interaction of Caldolor and Tacrine and the possibility of their joint administration.

Check result:
Caldolor <> Tacrine
Relevance: 20.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

An isolated case has been reported in which delirium was associated with the combined use of tacrine and ibuprofen. The mechanism of this interaction has not been determined. When tacrine and ibuprofen are used together, clinical monitoring for evidence of delirium may be warranted.

References
  • Hooten WM, Pearlson G "Delirium caused by tacrine and ibuprofen interaction." Am J Psychiatry 153 (1996): 842
Caldolor

Generic Name: ibuprofen

Brand name: Caldolor, NeoProfen, Advil, Advil Liqui-Gels, Midol, Motrin, Motrin IB, Motrin Migraine Pain, Proprinal, Smart Sense Children's Ibuprofen, PediaCare Children’s Pain Reliever/Fever Reducer, PediaCare Infant’s Pain Reliever/Fever Reducer, Genpril, Ibu, Midol IB, Children's Motrin, Motrin Junior Strength

Synonyms: n.a.

Tacrine

Generic Name: tacrine

Brand name:

Synonyms: Tacrine (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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