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Cambia and Phenobarbital Oral Solution

Determining the interaction of Cambia and Phenobarbital Oral Solution and the possibility of their joint administration.

Check result:
Cambia <> Phenobarbital Oral Solution
Relevance: 02.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Phenobarbital toxicity has been reported in a patient following initiation of diclofenac. The mechanism and clinical significance of this possible interaction is unknown. If these two drugs must be coadministered, the patient should be observed closely for phenobarbital toxicity such as slowness, ataxia, nystagmus, reduced reflexes and coma. Phenobarbital serum concentrations may need to be more closely monitored.

References
  • "Product Information. Arthrotec (diclofenac-misoprostol)." Searle, Skokie, IL.
Cambia

Generic Name: diclofenac

Brand name: Cambia, Cataflam, Zipsor, Zorvolex, Voltaren, Voltaren-XR, Dyloject, also Cambia

Synonyms: n.a.

Phenobarbital Oral Solution

Generic Name: phenobarbital

Brand name: Solfoton, Luminal

Synonyms: Phenobarbital, PHENobarbital

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction