Camptosar and Oxaliplatin Intravenous
Determining the interaction of Camptosar and Oxaliplatin Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using oxaliplatin together with irinotecan has been reported to occasionally increase side effects such as runny nose, watery eyes, blurry vision, excessive salivation, sweating, flushing, abdominal cramps, and diarrhea. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Several case reports have suggested that coadministration of oxaliplatin may increase the incidence and/or severity of irinotecan-induced cholinergic syndrome. The mechanism is unknown.
MANAGEMENT: Patients should be monitored for cholinergic symptoms (e.g., rhinitis, miosis, lacrimation, hypersalivation, diaphoresis, flushing, abdominal cramps, and diarrhea). Subcutaneous atropine has been used to prevent and treat symptoms.
- Cvitkovic E, Marty M, Wasserman E, Cuvier C, Goldwasser F, Misset JL "Re: Irinotecan-related cholinergic syndrome induced by coadministration of oxaliplatin." J Natl Cancer Inst 90 (1998): 1016-7
- Dodds HM, Bishop JF, Rivory LP "More about: irinotecan-related cholinergic syndrome induced by coadministration of oxaliplatin." J Natl Cancer Inst 91 (1999): 91-2
- Valencak J, Raderer M, Kornek GV, Henja MH, Scheithauer W "Irinotecan-related cholinergic syndrome induced by coadministration of oxaliplatin." J Natl Cancer Inst 90 (1998): 160
Generic Name: oxaliplatin
Brand name: Eloxatin
Synonyms: Oxaliplatin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Camptosar-Oxandrin
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- Oxaliplatin Intravenous-Camrese
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- Oxaliplatin Intravenous-Camrese Lo
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