Candesartan and Hydrochlorothiazide and Lofexidine Hydrochloride
Determining the interaction of Candesartan and Hydrochlorothiazide and Lofexidine Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Lofexidine and hydroCHLOROthiazide may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The hypotensive effects of lofexidine and antihypertensive agents may be additive. Postural hypotension may occur.
MANAGEMENT: Hemodynamic responses should be monitored during coadministration of lofexidine with antihypertensive agents, especially during the first few weeks of therapy.
- "Product Information. Lucemyra (lofexidine)." US WorldMeds LLC, Louisville , KY.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: candesartan / hydrochlorothiazide
Brand name: Atacand HCT
Synonyms: Hydrochlorothiazide and candesartan
Generic Name: lofexidine
Brand name: Lucemyra
Synonyms: Lofexidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Candesartan and Hydrochlorothiazide-Lofibra
- Candesartan and Hydrochlorothiazide-Lofibra Capsules
- Candesartan and Hydrochlorothiazide-LoHist PD
- Candesartan and Hydrochlorothiazide-LoHist-D
- Candesartan and Hydrochlorothiazide-LoHist-DM
- Candesartan and Hydrochlorothiazide-LoKara
- Lofexidine Hydrochloride-Candesartan and Hydrochlorothiazide Tablets
- Lofexidine Hydrochloride-Candesartan Cilexetil
- Lofexidine Hydrochloride-CanesOral
- Lofexidine Hydrochloride-Canges-XP
- Lofexidine Hydrochloride-Cangrelor
- Lofexidine Hydrochloride-Cangrelor Intravenous