Capozide 50/15 and Pentostatin Intravenous

• Generic Name: captopril / hydrochlorothiazide
• Dosage Forms: n.a.
• Other Brand Names: Capozide 25/15, Capozide 25/25, Capozide 50/15, Capozide 50/25

Captopril and hydrochlorothiazide combination is used to treat high blood pressure (hypertension). High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney failure. Hypertension may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Captopril works by blocking an enzyme in the body that is necessary to produce a substance that causes blood vessels to tighten. As a result, the blood vessels relax. Hydrochlorothiazide works by helping reduce the amount of salt and water in the body by acting on the kidneys to increase the flow of urine. Both of these medicines lower blood pressure and increase the supply of blood and oxygen to the heart .

This medicine is available only with your doctor's prescription .

• Generic Name: pentostatin
• Dosage Forms: n.a.
• Other Brand Names: Nipent

Pentostatin belongs to the group of medicines called antimetabolites. It is used to treat a type of cancer of the white blood cells called hairy cell leukemia. Pentostatin may be used in patients with hairy cell leukemia who have already been treated with other medicines (e.g., alpha-interferon) that did not work well.

Pentostatin interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by pentostatin, other effects may also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with pentostatin, you and your doctor should talk about the good pentostatin will do as well as the risks of using it.

Pentostatin is to be administered only by or under the immediate supervision of your doctor.