Carbamazepine and Safinamide Mesylate

• Generic Name: carbamazepine
• Dosage Forms: n.a.
• Other Brand Names: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Carbamazepine is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and nerve pain, such as tregimenal neuralgia and diabetic neuropathy.

Carbamazepine is also used to treat bipolar disorder.

Carbamazepine may also be used for purposes not listed in this medication guide.

• Generic Name: safinamide
• Dosage Forms: n.a.
• Other Brand Names: Xadago

Used as an adjunct to levodopa-carbidopa for the symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]) in patients who experience “off” episodes (i.e., time when drug effect wears off and parkinsonian manifestations return).

Shown to be effective only in combination with levodopa-carbidopa; efficacy of safinamide monotherapy not established.