Carbamazepine Extended-Release Capsules (Carbatrol) and Clonazepam Tablet Orally Disintegrating
Determining the interaction of Carbamazepine Extended-Release Capsules (Carbatrol) and Clonazepam Tablet Orally Disintegrating and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:CarBAMazepine may reduce the blood levels and effects of clonazePAM. You may need a dose adjustment if you have been taking clonazePAM and are starting treatment with carBAMazepine. Let your doctor know if clonazePAM becomes less effective or is no longer controlling your symptoms. In addition, using these medications together may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience some impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Carbamazepine may reduce serum clonazepam levels. The mechanism may be related to induction of metabolism. The risk of CNS-depressant side effects, such as sedation and apathy, may be increased with this combination.
MANAGEMENT: If these drugs must be used together, observation for clinical and laboratory evidence of altered clonazepam effect is recommended.
- Lai AA, Levy RH, Cutler RE "Time-course of interaction between carbamazepine and clonazepam in normal man." Clin Pharmacol Ther 24 (1978): 316-23
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Klonopin (clonazepam)." Roche Laboratories, Nutley, NJ.
Generic Name: carbamazepine
Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR
Synonyms: Carbamazepine, CarBAMazepine
Generic Name: clonazepam
Brand name: Klonopin, Klonopin Wafer
Synonyms: Clonazepam, ClonazePAM
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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