Carbamazepine Extended-Release Capsules (Carbatrol) and Epidiolex Oral Solution

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

CarBAMazepine may reduce the blood levels of cannabidiol, which may make the medication less effective in treating your condition. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSE: Coadministration with potent inducers of CYP450 2C19 and/or CYP450 3A4 may decrease the plasma concentrations of cannabidiol, which is primarily metabolized by these isoenzymes in the liver and gut.

MANAGEMENT: Dosage increase of cannabidiol may be required when coadministered with potent inducers of CYP450 2C19 and/or CYP450 3A4 based on clinical response and tolerability.

Carbamazepine Extended-Release Capsules (Carbatrol)

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: Carbamazepine, CarBAMazepine

What is Carbamazepine Extended-Release Capsules (Carbatrol)?

Epidiolex Oral Solution

Generic Name: cannabidiol

Brand name: Epidiolex

Synonyms: Epidiolex

What is Epidiolex Oral Solution?