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Carbamazepine Extended-Release Capsules (Carbatrol) and Vermox

Determining the interaction of Carbamazepine Extended-Release Capsules (Carbatrol) and Vermox and the possibility of their joint administration.

Check result:
Carbamazepine Extended-Release Capsules (Carbatrol) <> Vermox
Relevance: 10.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Carbamazepine may decrease plasma levels of mebendazole. The mechanism is unknown. Since mebendazole plasma levels vary greatly among patients receiving this drug, the clinical significance of this interaction is not well established.

References
  • Bekhti A, Pirotte J, Woestenborghs R "A correlation between serum mebendazole concentrations and the aminopyrine breath test: implications in the treatment of hyatid disease." Br J Clin Pharmacol 21 (1986): 223-6
  • Luder PJ, Siffert B, Witassek F, Meister F, Bircher J "Treatment of hydatid disease with high oral doses of membendazole." Eur J Clin Pharmacol 31 (1986): 443-8
Carbamazepine Extended-Release Capsules (Carbatrol)

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: Carbamazepine, CarBAMazepine

Vermox

Generic Name: mebendazole

Brand name: Vermox, Emverm

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.