Carbamazepine Extended-Release Capsules (Equetro) and Zyprexa
Determining the interaction of Carbamazepine Extended-Release Capsules (Equetro) and Zyprexa and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using carBAMazepine together with OLANZapine can cause side effects such as tremor (uncontrolled shaking), trouble walking, drooling, and restless muscle movements in your eyes, tongue, jaw, or neck. Talk with your doctor before using these medications together. You may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The manufacturer reports that carbamazepine (200 mg bid) may increase the clearance of olanzapine by as much as 50%. The mechanism is related to induction of CYP450 activity.
MANAGEMENT: Close clinical monitoring for evidence of altered olanzapine effect is recommended in patients receiving carbamazepine. Patients should be advised to report symptoms such as excessive drowsiness, slurred speech, or extrapyramidal symptoms, or agitation.
- "Product Information. Tegretol (carbamazepine)." Novartis Pharmaceuticals, East Hanover, NJ.
Generic Name: carbamazepine
Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR
Synonyms: Carbamazepine, CarBAMazepine
Generic Name: olanzapine
Brand name: Zyprexa, Zyprexa Zydis, Zyprexa Intramuscular, Zyprexa Relprevv
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Carbamazepine Extended-Release Capsules (Equetro)-ZyPREXA injection
- Carbamazepine Extended-Release Capsules (Equetro)-Zyprexa Intramuscular
- Carbamazepine Extended-Release Capsules (Equetro)-Zyprexa Relprevv
- Carbamazepine Extended-Release Capsules (Equetro)-Zyprexa Zydis
- Carbamazepine Extended-Release Capsules (Equetro)-Zyrtec
- Carbamazepine Extended-Release Capsules (Equetro)-Zyrtec (Cetirizine Capsules and Tablets)
- Zyprexa-Carbamazepine Extended-Release Tablets
- Zyprexa-Carbamazepine Intravenous
- Zyprexa-Carbamazepine Oral Suspension
- Zyprexa-Carbamazepine Tablets
- Zyprexa-Carbaphen 12
- Zyprexa-Carbaphen CH