Carbamazepine Oral Suspension and Tramadol Extended-Release Capsules and Tablets
Determining the interaction of Carbamazepine Oral Suspension and Tramadol Extended-Release Capsules and Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using traMADol together with carBAMazepine. Using these medications together may decrease the effects of traMADol. Contact your doctor if your condition changes or if you experience any other mental status changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Concomitant administration of carbamazepine increases tramadol metabolism, resulting in decreased serum concentrations and decreased efficacy. The suggested mechanism is CYP450 metabolic induction by carbamazepine. In addition, tramadol may increase the risk of seizures.
MANAGEMENT: Concomitant use of tramadol and carbamazepine is not recommended.
- Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL: http://www.appco.com.au/appguide/default.asp." ([2006]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Ultram (tramadol)." McNeil Pharmaceutical, Raritan, NJ.
Generic Name: carbamazepine
Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR
Synonyms: Carbamazepine, CarBAMazepine
Generic Name: tramadol
Brand name: ConZip, Ultram, Ultram ER, Rybix ODT, Ryzolt
Synonyms: Tramadol, TraMADol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Carbamazepine Oral Suspension-Trametinib
- Carbamazepine Oral Suspension-Trametinib Dimethyl Sulfoxide
- Tramadol Extended-Release Capsules and Tablets-Carbamazepine Tablets
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- Tramadol Extended-Release Capsules and Tablets-Carbaphen CH
- Tramadol Extended-Release Capsules and Tablets-Carbaphen Ped CH
- Tramadol Extended-Release Capsules and Tablets-Carbastat
- Tramadol Extended-Release Capsules and Tablets-Carbatrol