About us Contacts Drug interactions: 390 212
Drug search by name

Carbamazepine Oral Suspension and Zofran (Ondansetron Oral Solution)

Determining the interaction of Carbamazepine Oral Suspension and Zofran (Ondansetron Oral Solution) and the possibility of their joint administration.

Check result:
Carbamazepine Oral Suspension <> Zofran (Ondansetron Oral Solution)
Relevance: 23.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using carBAMazepine together with ondansetron can decrease the effects of ondansetron. Contact your doctor if you experience an increase in nausea and vomiting. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Concomitant use of CYP450 3A4 inducers with ondansetron may result in a reduced antiemetic effect, particularly after the oral administration of ondansetron. The proposed mechanism is induction of the CYP450 3A4 mediated metabolism of ondansetron. The clinical significance is unknown.

MANAGEMENT: Patients should be monitored for reduced antiemetic effects and the ondansetron dose adjusted as necessary.

References
  • "Multum Information Services, Inc. Expert Review Panel"
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Carbamazepine Oral Suspension

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: Carbamazepine, CarBAMazepine

Zofran (Ondansetron Oral Solution)

Generic Name: ondansetron

Brand name: Zofran, Zofran ODT, Zuplenz

Synonyms: Zofran

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.