Carbidopa and Yondelis

• Generic Name: carbidopa
• Dosage Forms: n.a.
• Other Brand Names: Lodosyn

Carbidopa is used with another medicine called levodopa to treat the symptoms of Parkinson's disease (stiffness, tremors, spasms, poor muscle control). Symptoms of Parkinson's disease may be caused by low levels of a chemical called dopamine (DOE pa meen) in the brain.

Levodopa is converted to dopamine in the brain. Carbidopa helps prevent the breakdown of levodopa before it can reach the brain and take effect.

Carbidopa is only used in combination with levodopa. Carbidopa has no effect when used alone.

Carbidopa is also used with levodopa to treat muscle symptoms similar to Parkinson's disease that are caused by certain drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Carbidopa may also be used for purposes not listed in this medication guide.

• Generic Name: trabectedin
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Yondelis

Yondelis (trabectedin) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Yondelis is used to treat liposarcoma, a rare type of cancer that grows in fatty tissues of the body.

Yondelis is also used to treat leiomyosarcoma, a rare fast-growing type of cancer that grows in many tissues of the body, including fat, muscle, bone, joints, and blood vessels.

Yondelis is used to treat cancer that has spread to other parts of the body or cannot be treated with surgery.