Drug search by name

Carbidopa and levodopa Route Not Applicable and Methyldopa

Determining the interaction of Carbidopa and levodopa Route Not Applicable and Methyldopa and the possibility of their joint administration.

Check result:

Carbidopa and levodopa Route Not Applicable <> Methyldopa

Relevance: 03.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Levodopa may enhance the antihypertensive effect of methyldopa. Data are conflicting regarding the benefit of adding methyldopa to the medical regimen of patients who have Parkinson's disease and who are already receiving levodopa. Some patients improve, but others worsen. Clinicians should be aware that combination therapy increases the risk of hypotension and that its effectiveness is unpredictable in patients with Parkinson's disease.

References

Gibberd FB, Small E "Interaction between levodopa and methyldopa." Br Med J 2 (1973): 90-1
Mones RJ "Evaluation of alpha methyl dopa and alpha methyl dopa hydrazine with L-dopa therapy." N Y State J Med 74 (1974): 47-51
Fermaglich J, Chase TN "Methyldopa or methyldopahydrazine as levodopa synergists." Lancet 1 (1973): 1261-2

Carbidopa and levodopa Route Not Applicable

Generic Name: carbidopa / levodopa

Brand name: Parcopa, Rytary, Sinemet, Sinemet CR, Duopa

Synonyms: Carbidopa and levodopa, Carbidopa and Levodopa

What is Carbidopa and levodopa Route Not Applicable?

Methyldopa

Generic Name: methyldopa

Brand name: Aldomet

Synonyms: n.a.

What is Methyldopa?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions