Carbidopa, Levodopa and Entacapone and Reserpine
Determining the interaction of Carbidopa, Levodopa and Entacapone and Reserpine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that reserpine may block the antiparkinsonian effects of levodopa. The mechanism is believed to be reserpine-induced depletion of brain dopamine. There is little clinical evidence for this theoretical interaction. In general, however, alternative antihypertensive therapy is recommended for patients in whom levodopa is required.
- Bianchine JR, Sunyapridakul L "Interactions between levodopa and other drugs: significance in the treatment of Parkinson's disease." Drugs 6 (1973): 364-88
- Cotzias GC, Papavasiliou PS, Gellene R "L-dopa in Parkinson's syndrome." N Engl J Med 281 (1969): 272
Generic Name: carbidopa / entacapone / levodopa
Brand name: Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75, Stalevo
Synonyms: Carbidopa, entacapone, and levodopa, Levodopa, Carbidopa, and Entacapone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Carbidopa, Levodopa and Entacapone-Reserpine, hydralazine, and hydrochlorothiazide
- Carbidopa, Levodopa and Entacapone-Resinol topical
- Carbidopa, Levodopa and Entacapone-Resorcinol and sulfur Topical
- Carbidopa, Levodopa and Entacapone-Resorcinol topical
- Carbidopa, Levodopa and Entacapone-Respaire-30
- Carbidopa, Levodopa and Entacapone-Resperal-DM Drops
- Reserpine-Carbidopa, Levodopa and Entacapone Tablets
- Reserpine-Carbihist
- Reserpine-Carbinoxamine
- Reserpine-Carbinoxamine Extended-Release Suspension
- Reserpine-Carbinoxamine Liquid
- Reserpine-Carbinoxamine Maleate