Carbocaine 2% with Neo-Cobefrin and Syntocinon
Determining the interaction of Carbocaine 2% with Neo-Cobefrin and Syntocinon and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using oxytocin together with levonordefrin may cause significant elevations in blood pressure and increase the risk of hypertension. Blood pressure and heart rate should be closely monitored if these medications are used together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Concomitant use of oxytocic agents with sympathomimetic amines may increase the risk of hypertension due to additive vasoconstrictive effects. Severe hypertension and headache have been reported when oxytocin was given 3 to 4 hours following prophylactic administration of a vasoconstrictor in conjunction with caudal block anesthesia.
MANAGEMENT: Close monitoring of blood pressure is recommended during coadministration.
- "Product Information. Syntocinon (oxytocin)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: levonordefrin / mepivacaine
Brand name: Carbocaine 2% with Neo-Cobefrin, Polocaine Dental, Scandonest 2% L
Synonyms: n.a.
Generic Name: oxytocin
Brand name: Pitocin, Syntocinon
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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