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Carboplatin and Cetuximab Intravenous

Determining the interaction of Carboplatin and Cetuximab Intravenous and the possibility of their joint administration.

Check result:
Carboplatin <> Cetuximab Intravenous
Relevance: 18.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using cetuximab together with CARBOplatin can increase the risk of infections. Contact your doctor immediately if you experience fever, chills, sore throat, fatigue, body aches, difficulty breathing, or other flu-like symptoms during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The use of cetuximab in combination with platinum-based chemotherapy, has been associated with an increased frequency of severe leukopenia or severe neutropenia, as compared to platinum-based chemotherapy alone. The risk of infections, such as febrile neutropenia, pneumonia, and sepsis, may be increased. The risk is increased in the presence of skin lesions, mucositis, diarrhea, or other conditions that facilitate the development of infections.

MANAGEMENT: Caution is advised if cetuximab is used in combination with platinum-based chemotherapy. Patients should be monitored closely for hematologic abnormalities and infections.

References
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Carboplatin

Generic Name: carboplatin

Brand name: Paraplatin, CARBOplatin Novaplus

Synonyms: CARBOplatin

Cetuximab Intravenous

Generic Name: cetuximab

Brand name: Erbitux

Synonyms: Cetuximab

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction