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Carboplatin and Dimethyl fumarate

Determining the interaction of Carboplatin and Dimethyl fumarate and the possibility of their joint administration.

Check result:

Carboplatin <> Dimethyl fumarate

Relevance: 18.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.GENERALLY AVOID: The use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents may increase the risk of infections. Both diroximel fumarate and dimethyl fumarate alone may cause lymphopenia and serious infections, and the risk may theoretically be increased due to additive immune system effects in the presence of other myelo- or immunosuppressive therapies. MANAGEMENT: The safety and efficacy of diroximel fumarate or dimethyl fumarate in combination with other immunosuppressive agents have not been evaluated. Until further information is available, the use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents should be avoided. References "Product Information. Vumerity (diroximel fumarate)." Alkermes, Inc, Cambridge, MA.

Professional:

GENERALLY AVOID: The use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents may increase the risk of infections. Both diroximel fumarate and dimethyl fumarate alone may cause lymphopenia and serious infections, and the risk may theoretically be increased due to additive immune system effects in the presence of other myelo- or immunosuppressive therapies.

MANAGEMENT: The safety and efficacy of diroximel fumarate or dimethyl fumarate in combination with other immunosuppressive agents have not been evaluated. Until further information is available, the use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents should be avoided.

References

"Product Information. Vumerity (diroximel fumarate)." Alkermes, Inc, Cambridge, MA.

Carboplatin

Generic Name: carboplatin

Brand name: Paraplatin, CARBOplatin Novaplus

Synonyms: CARBOplatin

What is Carboplatin?

Dimethyl fumarate

Generic Name: dimethyl fumarate

Brand name: Tecfidera, Tecfidera Starter Pack

Synonyms: Dimethyl Fumarate

What is Dimethyl fumarate?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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