Carboplatin and Furosemide Tablets

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using CARBOplatin together with furosemide may increase the risk of kidney damage and hearing loss. These effects may be more likely to occur in older adults or those with preexisting kidney problems or dehydration, or when high dosages of one or both medications are used. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. Keep yourself hydrated by drinking plenty of fluids unless otherwise directed. Let your doctor know if you experience ringing in the ears or hearing loss, or signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: The concomitant use of loop diuretics with carboplatin may increase the risk of ototoxicity. Loop diuretics, especially ethacrynic acid and high doses of furosemide, and platinum compounds have been individually associated with ototoxicity. Carboplatin is generally considered to be less neurotoxic and ototoxic than cisplatin; however, hearing loss has been reported when pediatric patients received high doses of carboplatin with other ototoxic agents.

MANAGEMENT: It is recommended to regularly monitor auditory function if concomitant use is necessary. Patients should be advised to promptly notify their physician if they experience hearing loss or tinnitus.

Carboplatin

Generic Name: carboplatin

Brand name: Paraplatin, CARBOplatin Novaplus

Synonyms: CARBOplatin

What is Carboplatin?

Furosemide Tablets

Generic Name: furosemide

Brand name: Lasix, Diaqua-2, Lo-Aqua

Synonyms: Furosemide

What is Furosemide Tablets?