Carboplatin and Kepivance

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Palifermin is used to treat painful mouth ulcers that can occur from chemotherapy. However, the timing of the dosing of palifermin relative to chemotherapy is important. Palifermin should generally not be used within 24 hours before or after chemotherapy. Otherwise, the mouth ulcers may actually worsen or heal more slowly. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: In a clinical trial, administration of palifermin within 24 hours of chemotherapy resulted in increased severity and duration of oral mucositis, presumably due to increased sensitivity of the rapidly dividing epithelial cells in the immediate post-chemotherapy period.

MANAGEMENT: Palifermin should not be administered within 24 hours before, during infusion of, or within 24 hours after administration of myelotoxic chemotherapy.

Carboplatin

Generic Name: carboplatin

Brand name: Paraplatin, CARBOplatin Novaplus

Synonyms: CARBOplatin

What is Carboplatin?

Kepivance

Generic Name: palifermin

Brand name: Kepivance

Synonyms: n.a.

What is Kepivance?