Carboplatin and Thioplex

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using CARBOplatin together with thiotepa. This combination can increase the blood levels or add to the medication side effects of CARBOplatin. You may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Thiotepa may intensify the toxicity of other alkylating agents (or radiation) rather than enhance therapeutic response.

MANAGEMENT: It is not advisable to combine chemotherapeutic agents (or modalities) that have the same mechanism of action. If these agents must follow each other, it is important that recovery from the first agent (or modality) be complete, as indicated by white blood cell count, before therapy with a second agent (or modality) is instituted.

Carboplatin

Generic Name: carboplatin

Brand name: Paraplatin, CARBOplatin Novaplus

Synonyms: CARBOplatin

What is Carboplatin?

Thioplex

Generic Name: thiotepa

Brand name: Thioplex, Tepadina

Synonyms: n.a.

What is Thioplex?