Drug search by name

Carboplatin and Vancomycin Intravenous, Injection

Determining the interaction of Carboplatin and Vancomycin Intravenous, Injection and the possibility of their joint administration.

Check result:

Carboplatin <> Vancomycin Intravenous, Injection

Relevance: 18.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using vancomycin together with CARBOplatin can increase the risk of kidney and inner ear damage. These effects may be more likely to occur in older adults or those with preexisting kidney problems or dehydration, or when high dosages of one or both medications are used. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. Let your doctor know if you experience ringing in the ears, hearing loss, vertigo, or signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Increased adverse effects are possible when glycopeptide antibiotics are administered concomitantly with other potentially nephrotoxic and neurotoxic drugs.

MANAGEMENT: If these drugs must be used together, renal function, auditory and vestibular function, and serum drug concentrations should be monitored.

References

Dubrovskaya Y, Prasad N, Lee Y, Esaian D, Figueroa DA, Tam VH "Risk factors for nephrotoxicity onset associated with polymyxin B therapy." J Antimicrob Chemother 70 (2015): 1903-7
Cerner Multum, Inc. "Australian Product Information." O 0
"Product Information. Vancocin (vancomycin)." Lilly, Eli and Company, Indianapolis, IN.

Carboplatin

Generic Name: carboplatin

Brand name: Paraplatin, CARBOplatin Novaplus

Synonyms: CARBOplatin

What is Carboplatin?

Vancomycin Intravenous, Injection

Generic Name: vancomycin

Brand name: FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, Vancocin, First-Vancomycin 25, First-Vancomycin 50

Synonyms: Vancomycin

What is Vancomycin Intravenous, Injection?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions