Cardioxane Injection and Effexor XR

• Generic Name: dexrazoxane
• Dosage Forms: injection, powder, for solution
• Other Brand Names: Totect, Zinecard

Dexrazoxane is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications.

The Totect brand of dexrazoxane is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun). Extravasation happens when an injected medicine escapes from the blood vessels and circulates into tissues in the body. Serious tissue damage can occur when extravasation happens during injection of certain cancer medications.

The Zinecard brand of dexrazoxane is used to help prevent chemotherapy-related heart problems in women who are receiving doxorubicin for metastatic breast cancer. Zinecard is given only after you have received enough doxorubicin infusions to amount to a certain total dose.

Dexrazoxane may also be used for purposes not listed in this medication guide.

• Generic Name: venlafaxine
• Dosage Forms: capsule, extended release
• Other Brand Names: Effexor XR, Effexor

Effexor XR is a selective serotonin and norepinephrine reuptake inhibitor (SNRIs) antidepressant. This medicine affects chemicals in the brain that may be unbalanced in people with depression.

Effexor XR is used to treat major depressive disorder, anxiety, and panic disorder.

Effexor XR may also be used for purposes not listed in this medication guide.