Cardizem Intravenous and Cobicistat
Determining the interaction of Cardizem Intravenous and Cobicistat and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Cobicistat may increase the blood levels and effects of dilTIAZem. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with cobicistat may increase the plasma concentrations of drugs that are substrates of the CYP450 3A4 or 2D6 isoenzymes and/or P-glycoprotein (P-gp) efflux transporter.
MANAGEMENT: Caution is advised if cobicistat is used concomitantly with medications that undergo metabolism primarily by CYP450 3A4 and/or 2D6 or are substrates of P-glycoprotein, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever cobicistat is added to or withdrawn from therapy.
- "Product Information. Stribild (cobicistat/elvitegravir/emtricitabine/tenofov)." Gilead Sciences, Foster City, CA.
Generic Name: diltiazem
Brand name: Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Diltzac, Matzim LA, Taztia XT, Tiazac, Cardizem CD, Dilt-XR, Tiazac, Cardizem LA, Tiazac Extended Release Capsules
Synonyms: Cardizem
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cardizem Intravenous-Cobicistat and darunavir
- Cardizem Intravenous-Cobicistat, darunavir, emtricitabine, and tenofovir
- Cardizem Intravenous-Cobicistat, elvitegravir, emtricitabine, and tenofovir
- Cardizem Intravenous-Cobimetinib
- Cardizem Intravenous-Cobimetinib Fumarate
- Cardizem Intravenous-Cobolin-M injection
- Cobicistat-Cardizem LA
- Cobicistat-Cardura
- Cobicistat-Cardura XL
- Cobicistat-Care One Acid Reducer Plus Antacid
- Cobicistat-Care One Sleep Aid
- Cobicistat-Careone Acid Reducer